We followed 48,775 Japanese National Health Insurance beneficiaries aged 40-79 years since 1994 for 11 years. We used Cox proportional hazard models adjusted for possible confounding factors. We also performed propensity for use of the health check-up matched cohort analyses. Compared to non-screenees, multiple-adjusted hazard ratios (95% confidence intervals) for all-cause and cardiovascular disease mortality among screenees were 0.74 (0.62-0.88) and 0.65 (0.44-0.95) for men and 0.69 (0.52-0.91) and 0.61 (0.36-1.04) for women, respectively. These relations were also observed when we used propensity matched cohort analyses. (宮城県大崎地区の住民を対象に追跡を行った前向きコホート研究において、48,775名を対象に健診・検診受診の受診歴とその後の死亡リスクとの関連について傾向スコアを用いて解析し報告した。傾向スコアを計算することにより対象者の特性を揃え、健診受診者と非受診者の死亡率の違いを算出した。健診非受診者に対する健診受診者の全死亡の相対危険度は0.71、循環器死亡の相対危険度は0.65であった。)
p.397-402
Hozawa A, Kuriyama S, Watanabe I, Kakizaki M, Ohmori-Matsuda K, Sone T, Nagai M, Sugawara Y, Nitta A, Li Q, Ohkubo T, Murakami Y, Tsuji I.
